first_imgMcGraw-Hill June 28, 2012 McGraw-Hill Construction has reported on May contracts for future construction in the state of Vermont. An authority on the construction market, the firm produces Dodge Reports and Sweets Catalog Files. According to the Research and Analytics unit of McGraw-Hill Construction, May’s construction activity followed this pattern: New Hampshire, meanwhile is only slightly below for the same time period:-Nonresidential buildings include commercial, manufacturing, educational, religious,administrative, recreational, hotel, dormitory and other buildings.-Residential buildings include one and two family houses and apartments.-Nonbuilding construction includes streets and highways, bridges,dams and reservoirs, river and harbor developments, sewage and water supplysystems, missile and space facilities, airports, utilities and communication systems.last_img read more

first_imgAfter several years of distinguished service to USA Triathlon (USAT) – highlighted by significant contributions to USAT’s information technology advances and, as Treasurer, oversight of USAT finances and investments – Jeff Matlow is resigning from his position on the National Board of Directors.Any current USAT annual member in good standing from the Southwest Region (Nevada, California and Arizona) may apply to fill that spot. The position will be filled based on a majority vote of the Board at its 30 May meeting in Colorado Springs. The individual appointed would serve on the Board for the remainder of 2009 and 2010 but would have to run for re-election in 2010, if he or she wanted to serve in 2011.Interested candidates should submit a platform statement of no more than 500 words, a brief r Relatedlast_img read more

first_imgABC News Radio:New research suggests that people who take dietary supplements may make worse decisions for their health than those who don’t.According to the study, published in Psychological Science, the action of taking supplements leads people to believe they are not susceptible to the health consequences of too little exercise or an unhealthy diet.Read the whole story: ABC News Radiolast_img

first_imgThe Wall Street Journal: Memory allows for a kind of mental time travel, a way for us to picture not just the past but also a version of the future, according to a growing body of research.The studies suggest that the purpose of memory is far more extensive than simply helping us store and recall information about what has already happened.Researchers from University College London and Harvard University have made strides charting how memory helps us draw a mental sketch of someone’s personality and imagine how that person might behave in a future social situation. They detailed their latest findings in work published in the journal Cerebral Cortex last week.…The body of work is “broadening out our view of how we use memory,” says Daniel Schacter, a psychology professor at Harvard.Read the whole story: The Wall Street Journal More of our Members in the Media >last_img read more

first_imgShare on Facebook Researchers from the MRC Centre for Developmental Neurobiology (MRC CDN) at King´s College London, led by Prof. Oscar Marín, have identified the mechanisms guiding interneurons to the striatum, a major brain centre involved in the coordination of body movement and motivation.These results, published in Journal of Neuroscience in collaboration with investigators from the Instituto de Neurociencias in Alicante (Spain), also reveal the molecule nature of the cues regulating the migration of striatal interneurons.During development, the medial ganglionic eminence (MGE), a transitory brain structure, produces several populations of GABAergic inhibitory neurons, including cortical and striatal interneurons. While most research studies have focused on the migration of interneurons to the cortex, very little is known about the mechanisms through which interneurons colonise the striatum. Both cortical and striatal interneurons can be attracted by Nrg1 sources present in the cerebral cortex and the striatum. Therefore, the segregation of these two populations of interneurons must depend on repulsive signals that prevent the colonization of regions outside their final target. LinkedIn Share Share on Twittercenter_img Email Experiments carried out by the group of Prof. Marín demonstrated that striatal interneurons are repelled by the cerebral cortex through a mechanism that involves Eph/ephrins signalling. This new study also showed that responsiveness of MGE-derived striatal interneurons to attractive and repulsive cues is at least in part controlled by the postmitotic activity of the transcription factor Nkx2-1. These results reveal parallel mechanisms of target chemoattraction and off-target chemorepulsion for the migration of interneurons to the cortex and striatum. Pinterestlast_img read more

first_imgWHO confirms 2 recent H7N9 cases in ChinaThe World Health Organization (WHO), citing Chinese officials, today confirmed two H7N9 avian flu cases reported by the media yesterday and provided further details.The first patient is a 3-year-old boy from Guangdong province who became sick Oct 29, was admitted to a local hospital on Oct 31, and was transferred to another hospital on Nov 4. He is in stable condition and had contact with live poultry, the WHO said.The second patient, a 64-year-old woman from Zhejiang province, is a farmer who also had contact with live poultry, the agency said. She became ill Oct 30, was admitted to a local hospital on Oct 31, and was transferred to another hospital on Nov 3, where she remains in critical condition.The two cases bring the total H7N9 count to 139 lab-confirmed cases and 45 deaths. Six of those patients still remain hospitalized, the WHO said.Nov 6 WHO statement Cargill to start labeling products that contain finely textured beefCargill Beef of Wayzata, Minn., yesterday announced that it will label beef products that contain finely textured beef, a product derogatorily labeled “pink slime” by critics last year, which led some retailers to pull products that contained it.”Our research shows that consumers believe ground beef products containing Finely Textured Beef should be clearly labeled,” said John Keating, Cargill Beef president, in a company news release. “We’ve listened to the public, as well as our customers, and that is why today we are declaring our commitment to labeling Finely Textured Beef.”The company said the labeling will be in place for the product “prior to the 2014 grilling season.” Finely textured beef consists of beef trimmings that are heated slightly, centrifuged to remove liquefied fat, and treated to kill bacteria. The process helps save meat that would otherwise be discarded, industry officials have said.Cargill said finely textured beef is 95% lean. It announced a Web site dedicated to providing information on the product.Last year the controversy caused South Dakota–based Beef Products Inc. (BPI) to close three of its four plants that made the product. Nov 5 Cargill news release May 8, 2012, CIDRAP News scan on BPI plant closings Doctors group: Focus measles response on youngest kidsMeasles outbreak response in Africa needs to focus on the youngest children, who are most affected, according to a report by Medecins Sans Frontieres (Doctors Without Borders) on a resurgence of the disease in sub-Saharan Africa, published yesterday in PLoS Medicine.The group compared and contrasted two measles outbreaks that accounted for most measles cases in the region in recent years. In the Democratic Republic of the Congo, 128,111 measles cases occurred in 2010 and 2011, including 1,454 deaths. Sixty percent of those cases occurred in Katanga province, which saw an attack rate (AR) of 0.71% and a case-fatality rate (CFR) of 1.40%.That contrasts with Malawi, which had 134,039 measles cases in 2010 but only 304 deaths. That country’s AR was 0.96%, but its CFR was only 0.23%.Age differences between the two outbreaks were dramatic. In Katanga, the median age of patients was 2 years, with 80% of reported case-patients 5 years old or younger and only 6% 10 years or older. In Malawi, the median age of patients was 7 years, with 41% of reported cases in children 5 years old or younger and 28% 15 years or older.”Differences in measles epidemiology and country-specific control goals necessitate more than a one-size-fits-all strategy,” the authors summarized. “The youngest children—who account for the most deaths and complications—should be prioritized by the outbreak response.”Nov 5 PLoS Med reportlast_img read more

first_imgNorthern Ireland announces One Health AMR planThe government of Northern Ireland yesterday announced a 5-year, One Health action plan to fight antimicrobial resistance (AMR).The plan, developed by Northern Ireland’s Department of Health and Department of Agriculture, Environment and Rural Affairs in collaboration with the United Kingdom’s Food Standards Agency (FSA), aims to address the growing threat of drug-resistant pathogens by lowering the burden of infection in humans and animals, optimizing antibiotic use on farms and in human medicine, strengthening AMR surveillance, minimizing the spread of AMR in the environment, and investing in research into new therapeutics and diagnostics.Among the specific goals laid out in the plan are a 10% reduction in the incidence of specific drug-resistant infections in people, a 50% reduction in healthcare-associated gram-negative bloodstream infections, and a 15% reduction in human antimicrobial use by 2023-2024.”This issue affects more than just human health and healthcare. Whenever we make an environment favourable for infectious bugs, then they take advantage,” Maria Jennings, FSA director in Northern Ireland, said in a press release. “This affects farming, the environment and ultimately the food we eat.  Taking a One Health approach and working with partners across government is the most effective way to address AMR.”The plan was developed in conjunction with the United Kingdom’s 20-year vision and 5-year national action plan for addressing AMR, released in January. May 16 Northern Ireland 5-year action plan May 16 Northern Ireland Executive press release Jan 24 CIDRAP News story, “UK aims to cut antibiotics 15% in 5-year plan” Rapid susceptibility test produces mixed results in German studyIntroduction of a novel, rapid antimicrobial susceptibility test at a German hospital significantly reduced time for species identification (ID) and antimicrobial susceptibility testing (AST) in patients with bloodstream infections, as well as time to optimal antimicrobial therapy, researchers at University of Cologne Hospital reported yesterday in Clinical Infectious Diseases. But the test did not affect antimicrobial consumption or clinical outcomes.In the quasi-experimental study, researchers investigated the impact of The Accelerate Pheno system (ADX), a new technology that identifies microorganisms from a positive blood culture within 90 minutes and provides phenotypic AST results within 7 hours, by analyzing three different groups of patients with a positive blood culture. One group was evaluated and treated with conventional diagnostics, a second with conventional diagnostics and antimicrobial stewardship program (ASP) intervention, and a third with ADX and ASP intervention. The goal was to see whether use of ADX leads to earlier therapeutic decision-making, decreased use of broad-spectrum antimicrobials, decreased length of hospitalization, and better clinical outcomes.Overall, 204 patients were evaluated; 64 in the conventional diagnostics group, 68 in the conventional diagnostics plus ASP group, and 72 rapid diagnostics plus ASP group. Compared with the two groups using conventional diagnostics, the use of ADX significantly decreased time from Gram stain to ID (median: 23 vs 2.2 hours, P < 0.001) and time to AST results (median: 23 vs 7.4 hours, P < 0.001) and shortened time from Gram stain to optimal antimicrobial therapy (median: 11 vs 7 hours, p < 0.024) and to step-down antimicrobial therapy (median: 27.8 vs 12 hours, P < 0.019). But no significant differences were found in the duration of antimicrobial treatment, total antimicrobial consumption, length of hospital stay, or 7-day and 28-day in-hospital mortality."In conclusion, the use of ADX significantly reduced time to ID and AST as well as time to optimal antimicrobial therapy but did not affect clinical outcome parameters," the authors of the study write. "It remains to be determined if a larger study in a high resistance setting or in a setting with 24/7 microbiology service or with less active ASP involvement can show lower mortality rates and antimicrobial consumption when rapid susceptibilities are provided."May 16 Clin Infect Dis abstract Study: Antibiotics for respiratory infections common in cancer patientsIn another study yesterday in Clinical Infectious Diseases, researchers with Fred Hutchinson Cancer Research Center found that nearly one-third of hematology-oncology patients were prescribed antibiotics for a respiratory tract infection. But viral causes were identified in 75% of patients tested, and viral testing was associated with reduced prescribing.The retrospective study looked at the electronic medical records of patients who presented for care at Seattle Cancer Care Alliance and had received a diagnosis for acute upper respiratory tract infection (URI) or acute bronchitis from October 2015 through September 2016. The researchers obtained antibiotic prescribing, viral testing, and other clinical data from the first clinical encounter for the URI through day 14 to characterize antibiotic prescribing patterns, use of respiratory viral diagnostic tests, and clinical outcomes associated with URI in an immunocompromised population.Of the 251 patients included in the final analysis, 81 (32%) were prescribed an antibiotic for URI symptoms, with 52 (64%) receiving prescriptions on day 0, 11 (14%) on days 1-2, and 18 (22%) on days 3-14. Viral testing was performed in 113 patients (45%), and at least one virus was detected in 85 (75%). Antibiotic prescribing and viral testing varied substantially by clinical service.On univariate analysis, sputum production or chest congestion were associated with higher risk of antibiotic prescribing (relative risk [RR], 2.3; 95% confidence interval [CI], 1.4 to 3.8, P < 0.001), while viral testing on day 0 was associated with lower risk of antibiotic prescribing (RR=0.4, 95% CI 0.2 to 0.8, P = 0.01), though collinearity between viral testing and clinical service limited the ability to separate these effects on prescribing. Antibiotic prescribing was not associated with subsequent URI-related healthcare visits (P = 0.89).The authors of the study conclude, "These findings highlight the need for further research to explore the role and cost-effectiveness of molecular respiratory viral testing in limiting unnecessary antibiotic use among hematology-oncology patients."May 16 Clin Infect Dis abstractlast_img read more

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first_imgThe first two letters on our letters page, taken together, perfectly illustrate the mindsets of East Hampton Airport opponents and proponents, and perhaps why such a controversial subject has lingered for so long — the inability of the hardliners to see both sides of the issue.The first, by Elliot Meisel, a member of the East Hampton Aviation Association, takes this newspaper to task, accusing us of publishing an “inflammatory article” that lacked “a balanced prospective.” Basically, our reporter T.E. McMorrow wrote a short article about a study by a consulting firm the town board commissioned regarding noise created by aircraft that use the local airport. He reported the numbers that were presented to the board. It was one of dozens of articles about the airport that have appeared in this newspaper over the years.Meisel complained McMorrow isn’t “a fair minded” reporter. The crux of his letter is that many of the people who complain about airport noise do so repeatedly. The Independent, in the past, has reported this at some length. The second half of his letter rehashed the mantra in effect for two decades: The airport generates jobs and revenue. We get that.The second letter writer, Robert Skinner, from Jamesport, tells a horror story of air traffic during the season over his house. It’s constant, it’s loud, it’s annoying, and he wants instead for helicopters to head to East Hampton by flying over Long Island Sound, circle Plum Island, and approach the airport from the northwest.Earlier in the summer we reported there was some impetus to allow pilots to take the southern route over the Atlantic beaches but they are stymied by fog and a control tower at the airport that was too short to see the aircraft.Thank you for writing the letters, and both of you are correct.We know a lot of complainers log an inordinate amount of calls. We’ve sent reporters to park outside their homes during the peak summer hours. Guess what? It’s noisy as hell.We believe asking pilots to fly 18 additional miles around Plum Island is inefficient, and history has shown once they start their inward flight path to East Hampton, they will once again rankle homeowners as they fly over — it will be different people, same complaint.It seems to us, local pilots, by and large, seem to get it. But the helicopter companies making obscene money by operating shuttle services need to be reeled in, or at the very least, brought to the negotiating table. Routes in and out of the airport should be varied, so that no one neighborhood is overwhelmed, though safety must always come first.One thing for sure: When the town pays a consultant to inform them noise complaints doubled in one year, it should also be told how many people are lodging complaints. One sometimes gets the impression the town board manipulates consultants to tell members what they want to hear. The habit of manipulating data to shape public opinion is unfortunately not a new phenomenon in this town. Sharelast_img read more