first_img Phoenix Business Consulting invests in telehealth platform Healpha WHO tri-regional policy dialogue seeks solutions to challenges facing international mobility of health professionals The missing informal workers in India’s vaccine story Menopause to become the next game-changer in global femtech solutions industry by 2025 Indraprastha Apollo Hospitals releases first “Comprehensive Textbook of COVID-19” Case Studies News Share MaxiVision Eye Hospitals launches “Mucormycosis Early Detection Centre” Azrieli National Institute for Human Brain Imaging and Researcholfactory bulbssense of smellWeizmann Institute of Science Some humans can smell just fine without olfactory bulbs: Weizmann Institute of Science researchers Related Posts By EH News Bureau on November 11, 2019 Read Article Add Comment Around 0.6 per cent of women, more specifically, up to 4 per cent of left-handed women, have completely intact senses of smell despite having no olfactory bulbs in their brainsIs a pair of brain structures called the olfactory bulbs, which are said to encode our sense of smell, necessary? That is, are they essential to the existence of this sense? Weizmann Institute of Science researchers recently showed that some humans can smell just fine, thank you, without olfactory bulbs. Their finding – that around 0.6 per cent of women, and more specifically, up to 4 per cent of left-handed women, have completely intact senses of smell despite having no olfactory bulbs in their brains – calls into question the accepted notion that this structure is absolutely necessary for the act of smelling. The findings of this research, which were published recently in Neuron, may shake up certain conventional theories that describe the workings of our sense of smell.In the majority of people who have functioning olfactory bulbs, nerve signals from receptors in the nose go first through the bulbs before being passed onwards toward the olfactory centre in the cortex. The prevailing theory has the olfactory bulbs combining the information from the six million receptors in our noses, of some 400 different types, and encoding a unique “odour” signal to be passed on. Thus, unsurprisingly, some people who are congenitally anosmic ‒ that is, they never had a sense of smell ‒ indeed have no olfactory bulbs.Although the centrality of the olfactory bulbs in olfactory perception is the “textbook” view, in the 1980s and 1990s some researchers had removed the olfactory bulbs from the brains of rodents and found their sense of smell to remain functional. These findings, however, were not well received in the scientific community.The new findings were unexpected: Dr Tali Weiss and Dr Sagit Shushan in the lab of Prof Noam Sobel of the Institute’s Neurobiology Department were conducting MRI scans of subject’s brains in the Azrieli National Institute for Human Brain Imaging and Research on campus. One of the subjects, who had stated her sense of smell was normal, was found to be lacking olfactory bulbs in her brain. The subject insisted: Her sense of smell was not only normal, it was excellent. “We tested her smelling faculties in every way would could think of, and she was right,” says Sobel. “Her sense of smell was indeed above average. And she really doesn’t have olfactory bulbs. We conducted another scan with especially high-resolution imaging, and saw no signs of this structure.”At first the researchers, led by Weiss and research student Timna Soroka, thought this might be the sort of exception that does not disprove the rule. They took functional MRI (fMRI) scans of her brain and compared them with those of a control group. But they needed a unique control group. Since the subject was female and left-handed – both traits that can influence the organisation of the brain – the researchers invited other left-handed women to have their brains scanned for comparison. “When the ninth subject in the ‘control’ group also turned out to be lacking olfactory bulbs, alarm bells started ringing,” says Weiss.The olfactory bulb, at around 58 mm cubed in volume, is visible to the naked eye in images, but, says Sobel, if someone is not specifically looking for this structure, they are liable to miss it – or to miss its absence. And because the differences connected to handedness can complicate datasets, some researchers even stick to right-handers, assuming their findings on such things as the olfactory system will be relevant to left-handers as well.And yet once they started looking for evidence for this phenomenon, the research team found it in an existing database: that of the Human Connectome Project. Out of the 1113 brain scans in this database, many of them of identical twins, some 10 per cent are from left-handed individuals (around their incidence in the general population). And among the records contained in this open database are the results of smell tests given to the subjects. Weiss and Soroka, with the help of Liav Tagania, a high school student working on an educational project in Sobel’s lab, searched through the information in the database. They did not find a single male who had both an intact sense of smell and a missing olfactory bulb, but they did find four women with both. Of those four women, two were left-handed. “Even more amazing was the fact that the two left-handed women were identical twins, and their twin sisters did have olfactory bulbs. Each of those with no olfactory bulb in their brains scored better on the smell test than their intact twin sisters,” says Soroka.How do these “exceptions to the rule” square with the commonly held view of the sense of smell? There are several possible explanations. One is that the highly plastic brain creates a “smell map” in a different part of these women’s brains. But another possible explanation is that these exceptions do disprove the rule. “Current ideas posit the olfactory bulb as a ‘processing centre’ for information that is complex and multi-dimensional, but it may be that our sense of smell works on a simpler principle, with fewer dimensions. It will take high resolution imaging – higher than that approved for use on humans today – to resolve that issue,” says Sobel. “But the fact remains that these women smell the world in the same way as the rest of us, and we don’t know how they achieve this.” Comments (0) Heartfulness group of organisations launches ‘Healthcare by Heartfulness’ COVID care applast_img read more

first_imgGet your free guest access  SIGN UP TODAY To continue enjoying Building.co.uk, sign up for free guest accessExisting subscriber? LOGIN Subscribe now for unlimited access Stay at the forefront of thought leadership with news and analysis from award-winning journalists. Enjoy company features, CEO interviews, architectural reviews, technical project know-how and the latest innovations.Limited access to building.co.ukBreaking industry news as it happensBreaking, daily and weekly e-newsletters Subscribe to Building today and you will benefit from:Unlimited access to all stories including expert analysis and comment from industry leadersOur league tables, cost models and economics dataOur online archive of over 10,000 articlesBuilding magazine digital editionsBuilding magazine print editionsPrinted/digital supplementsSubscribe now for unlimited access.View our subscription options and join our communitylast_img read more

first_imgOnce again, the media in Italy report that it is possible that Lionel Messi will play in Serie A with the Inter team. This time the assumption is based on the information that his father – Jorge Messi, bought a house in Milan.The news was first announced by Radio Rai, and then it reached the front page of Gazzetta dello Sport. The Nerazzurri have not hidden their interest in the Barcelona megastar for years, and recently one of their main sponsors expressed readiness to finance a possible deal.According to Sky Sport Italia, however, this is not a potential transfer at all, but a move by Messi Sr. from a purely financial point of view. For three years now, Italy has been offering much lower taxes to wealthy foreigners who buy a mansion in the country, writes Focus. Leo has already entered the last year of his contract with the Catalans and negotiations for a new one are still not underway.last_img read more

first_imgShare This!Epcot’s International Food and Wine Festival is right around the corner. What else is right around the corner? Lines for the food booths on the first Saturday afternoon of the festival. With so many booths to choose from, but lines being almost guaranteed at most, how do you know what is worth waiting for and what can be skipped during peak times? Here’s my views from sampling all the foods last year and eagerly anticipating the new ones.If you’re just looking for the highlights, you might want to check out my Top Ten Returning Items.*Indicates item returning from last year.Africa *Grilled Sweet and Spicy Bush Berry Shrimp with Pineapple, Pepper, Onion and Snap Peas (Pictured)*Grilled Lamb Chop with Mint Pesto and Potato Crunchies*Lamington: Yellow Cake Dipped in Chocolate and Shredded CoconutThe dish most people will be talking about is the grilled lamb chop, which tends to be a festival favorite. For me, I find eating a lamb chop on the go a little awkward, as it just doesn’t seem right to pick up the bone and gnaw on it like one would do with a turkey leg. It feels a little better to grab the shrimp by the tail and eat them, although it is messy with the sweet and spicy sauce. The vegetables in that dish feel like an afterthought. The Lamington is the one dish I want to  love, but every time I got it, the cake was horrifically dry. If that trend continues, it is a dessert to skip.Belgium *Canadian Cheddar Cheese Soup*”Le Cellier” Wild Mushroom Beef Filet Mignon with Truffle Butter Sauce (Pictured)Nothing says high-class like eating filet mignon out of a paper tray with plastic cutlery? Although the beef is delicious, it isn’t the easiest food to eat on the go, and the price can cause a bit of sticker shock. For that reason, this is on my list of foods to skip. The cheddar cheese soup is always a favorite, and with the reported inclusion of a pretzel roll this year, this wonderful dish is even better.The Chew Collective *Charcuterie Plate: Country Pate, Cured Meats, and Crostini (Pictured)*Pimento Cheese Dip with Pretzel ChipsPiggy Wings: Fried Pork Wings with Korean BBQ Sauce and Sesame SeedsLet’s face it–the main attraction at the Craft Beers booth is not going to be the food. Unless you really need something to chow down on while you sample beers, you can skip the returning foods from last year. I am intrigued by the idea of “fried pork wings”. Did someone say “Hey, we need to have good food at Craft Beers” and someone responded “That’ll happen when pigs fly”? In my mind, I’m thinking this may develop some sort of secret McRib-like cult following. Only time will tell.Stay tuned for the next exciting post with some returning favorites and some new booths to sample.Any of these foods your returning favorites? Are any going on your must try or must skip list? Feel free to sound off in the comments. *Escondidinho de Carne (Layered Meat Pie with Mashed Yucca)*Crispy Pork Belly with Black Beans and Tomato*Brazilian Cheese Bread (Pictured)Every year, my order at the Brazil booth is the same: One of each of the foods, please. There’s nothing at the booth I wouldn’t recommend, and it is no surprise that I stop there several times during the festival. Whether you sample one food at a time or go for everything at once, this booth has some of the most consistently best food at Food and Wine.Canada Ghirardelli Chocolate Raspberry TorteRed Wine Chocolate Truffle*Liquid Nitro Chocolate Almond Truffle with Warm Whiskey Caramel (Pictured)Can I be the first to say that I’m quite thankful the small box of prepackaged chocolate seashells is no longer being offered? Don’t get me wrong, I love them, but prepackaged food just doesn’t fit with the festival booth vibe. What I’m most curious about is to see portion sizes and prices for the new chocolate offerings. One thing is for certain, I will be in line to get the Liquid Nitro truffle, returning from its debut last year at the Chew Lab booth. Foods made with liquid nitrogen are just plain cool. (Yes, you see what I did there.)Craft Beerscenter_img *Ricotta and Zucchini Ravioli with Rustic Tomato Sauce (Pictured)Grilled Beef Skewer with Romaine, Apricots, and Feta CheesePeanut Butter and White Chocolate Mousse with a Caramel DrizzleThe Chew Lab and Sustainable Chew have now merged into the equally awkward sounding “Chew Collective” booth. Two dishes from last year’s Chew booths are returning, and one of them will be found at the Collective–the ricotta and zucchini ravioli. My husband and I were split on this dish. He enjoyed the fresh flavors, but I thought it was a bit “soupy” in texture. I am excited about the other two dishes, and expect that the dessert offering will be a hit. The unique combination of flavors with the beef skewer will likely bit hit or miss for some people, but it is a flavor combination that I can get behind.China Beer-braised Beef with Smoked Gouda Mashed Potatoes*Belgian Waffle with Warm Chocolate Ganache and Whipped Cream (Pictured)*Belgian Waffle with Berry Compote and Whipped CreamNew this year is a beer-braised beef dish with smoked Gouda mashed potatoes, very similar to an offering last year, but now with 100% less waffle. Perhaps this makes a gluten-free dish at a formerly gluten-laden booth? Gouda is my favorite cheese, so I think this dish will be a winner. The other waffles are always delicious, but in the end, they are waffles with toppings. If you’re eating Mickey waffles during your trip or taking a visit to Sleepy Hollow in the Magic Kingdom for a Nutella waffle, is it worth it to sample the waffles here?Brazil *Berbere-style Beef Tenderloin Tips with Onions, Jalapenos, Tomato and Pap (Pictured)*Buttered Chicken with Micro Cilantro and Naan BreadPerhaps it is its location near the back of the park, or maybe it is because people either don’t feel “adventurous” enough to try African food (or those who do already have an ADR for Boma, Jiko, Sanaa. or Tusker House), but lines rarely seem to be too long for this booth. It’s a shame more people don’t give it a try, because the Buttered Chicken is one of my favorite meals. For a little more of a kick, the Beef Tenderloin Tips are good, but not as good as the chicken, in my opinion.Australia *Beijing Roasted Duck in a Steamed Bun with Hoisin Sauce (Pictured)Sichuan Spicy ChickenBlack Pepper Shrimp with Garlic Noodles*Chicken Pot StickersThe Sichuan flavors from the noodles that accompanied the black pepper shrimp have now been moved to a spicy chicken dish, making the black pepper shrimp a bit more approachable if you’re not a huge fan of spicy foods. Perhaps it is the Nine Dragons effect, but the China booth often gets a ho-hum response. Unless you’re really craving pot stickers, skip them–they’re on par with any Chinese takeout.Chocolate Studiolast_img read more

first_imgIndian cricket team skipper Mahendra Singh Dhoni riding a bullet on the streets of Ranchi. Photo: PTI.Mahendra Singh Dhoni has been penalised for violating traffic rule during his short stay in his home town here, a senior police officer on Wednesday said.Dhoni was slapped with a fine of Rs 450 for faulty display of number plate on his motorcycle, Superintendent of Police (Traffic) Karthik S said.The registration number of his bike was displayed in vertical manner on the mud guard of the front wheel, which is violation of the Motor Vehicles Act.Dhoni was charged for violation of section 179 of the Motor vehicles Act and section 50 and 51 of the Central Motor Vehicle rule, Karthik said.Ranchi Traffic Police has launched a drive since March 16 to strictly enforce number plate regulation on vehicles.As Dhoni had already left Ranchi to take part in the IPL-8, Karthik said the police spoke to his family members who agreed to pay the fine on his behalf.last_img read more

first_imgLiverpool defender Van Dijk: I’ve still much to improveby Paul Vegas9 months agoSend to a friendShare the loveLiverpool defender Virgil van Dijk says he’s far from the finished article.He has been named the Premier League’s Player of the Month award for December.And the Netherlands captain demands more of himself.“I’ve improved in every aspect of my game but there is still so much to learn and to get better at,” he said ahead of Saturday’s league meeting with Brighton and Hove Albion.“I’m working every day to get to where I want to be – I want to get the maximum out of myself. That’s [done] by working every day and making sure that you give everything for the team and for your club.” About the authorPaul VegasShare the loveHave your saylast_img read more

first_imgCollege Spun staff picks for week 12 of the 2015 college football season.college spun staff picks week 12Last week, four top ten teams – Baylor, Stanford, LSU and Utah – fell, further complicating the College Football Playoff picture. The Pac-12, which no longer features a team with less than two losses, is in trouble. The Big 12, meanwhile, is looking more likely to see one of its squads qualify for the event. And then there’s Notre Dame, which may very well finish 11-1 and find itself on the outside looking in.This week, despite most of the SEC scheduling cupcakes, we’ve got some great games. LSU takes on Ole Miss. USC and Oregon meet. Baylor and Oklahoma State will tangle. Oklahoma will look to stay hot against TCU. And of course, Michigan State heads to Columbus to take on Ohio State.Matt Hladik is still our leader, but he isn’t in the clear yet. Here’s who we have this week:week 12 picks 1week 12 picks 2week 12 picks 3Who do you have?last_img read more

first_imgMONTREAL – Canada’s Immigration Department says a murder suspect who was set free after his trial exceeded the legal length limit is expected to be sent back to Sri Lanka in the next two weeks.Ewa Staszewicz, a lawyer for the department, is confirming steps are being taken to obtain the necessary travel documents for Sivaloganathan Thanabalasingam.Thanabalasingam, 31, told an Immigration and Refugee Board of Canada hearing today he doesn’t believe he will be in danger in his home country and no longer needs to be protected as a refugee.He was accused of murdering his wife in 2012 but the charges were stayed in April after the length of his legal proceedings were deemed to have violated a Supreme Court of Canada ruling that set time limits for trials to be completed.He was detained by Canada Border Services Agency upon his release and a deportation order was issued against him.Thanabalasingam, who came to Canada as a refugee, originally appealed the deportation order but later changed his mind and asked to be sent back to Sri Lanka.There is still an appeal pending against Thanabalasingam as the Crown has challenged the judgment that halted the legal proceedings against him.last_img read more